Hydroxychloroquine is a well-established medication commonly used in the treatment of autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and sjögren’s syndrome. It works by modulating the immune system to reduce inflammation, joint pain, and flare-ups associated with these chronic conditions. While originally developed as an antimalarial drug, its immunomodulatory effects make it a key therapy in long-term autoimmune disease management.
The typical starting Dosage Hydroxychloroquine for adults with autoimmune disorders ranges between 200 mg to 400 mg per day, depending on the patient’s weight, disease severity, and medical history. In some cases, it may be prescribed as a single daily dose or split into two smaller doses to reduce stomach upset. Doctors generally aim to use the lowest effective dose to minimize side effects while maintaining therapeutic benefits.
Long-term treatment with hydroxychloroquine requires regular monitoring, especially of eye health. Since the drug can accumulate in retinal tissues, patients undergoing extended therapy should have an eye exam at baseline and annually thereafter to check for signs of retinal toxicity. This risk increases with higher doses or prolonged use beyond five years.
It’s essential to take hydroxychloroquine exactly as prescribed and not exceed the recommended dosage. Abruptly stopping the medication can lead to flare-ups or worsening of symptoms. Always consult your rheumatologist or healthcare provider for the appropriate dose and follow-up care tailored to your specific condition and response to treatment.

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